The drugs are also incorporated into newly formed bone and can persist in them for years, so the effects last well beyond the final treatment. Bisphosphonates decrease the rate that bone is destroyed, a process called resorption, by stopping the activity of the cells that cause bone breakdown, called osteoclasts. Some are taken daily others are formulated for weekly, monthly or yearly use. The FDA has approved many bisphosphonates to prevent bone loss and fractures in post-menopausal women: alendronate (brand name Fosamax), etidronate (brand name Didronel), ibandronate (brand name Boniva), risedronate (brand name Actonel), tiludronate (brand name Skelid), pamidronate (brand name Aredia) and zoledronic acid (brand names Reclast and Zometa). First Line Treatments Bisphosphonatesīisphosphonates are commonly prescribed for osteoporosis treatment and prevention. We hope this tool will help empower women to have conversations about osteoporosis with their providers, make informed decisions about whether they need drug treatment, and determine which drugs makes the most sense for their unique circumstances.
#BONE DISINTEGRATION HOW TO#
We’ve developed this to help women understand what treatment options exist, what the side effects and risks are, what evidence supports their efficacy, and how to adopt non-drug approaches to preventing fracture. Overall, efforts should focus on promoting bone health for all women and preventing fractures through a variety of methods for those at risk.
Though drugs can be appropriate for women with severe osteoporosis who are at high risk of fracture, they are not the solution for everyone. The NWHN believes that treatment should be focused on women who are known to be at high risk of fracture due to prior fractures, long-term corticosteroid use, or other known risk factors. This has created a dilemma for women trying to decide which, if any, of these medications they need. Now, there are many different types of treatments available. In the early 1990s, women had few treatment options. Osteoporosis treatment has radically changed in a relatively short period.
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